Ahikal
☆    

Egypt,
2021-12-24 18:41
(852 d 18:41 ago)

Posting: # 22716
Views: 1,874
 

 dissolution, passing f2 but failing f1 [Dissolution / BCS / IVIVC]

Post reply
hello all, in a dissolution comparison, I got f2>50, f1>15, and within batch CV<15%. I am befuddled, would appreciate any suggestion.
thanks
Ahmed
 
dshah
★★  

India/United Kingdom,
2021-12-29 11:28
(848 d 01:53 ago)

@ Ahikal
Posting: # 22719
Views: 1,520
 

 dissolution, passing f2 but failing f1

Post reply
Hello Ahmed!
Could you provide details for %CV? it seems that the dissolution is having higher %SD apart from 1st time point. Kindly try to evaluate other methods like Bootstrap/MSD.
Regards,
Dshah
 
UA Flag
Activity
 Admin contact
22,993 posts in 4,828 threads, 1,655 registered users;
94 visitors (0 registered, 94 guests [including 0 identified bots]).
Forum time: 14:22 CEST (Europe/Vienna)

Never never never never use Excel.
Not even for calculation of arithmetic means.    Martin Wolfsegger

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5