Ahikal
☆    

Egypt,
2021-12-24 18:41
(847 d 11:10 ago)

Posting: # 22716
Views: 1,862
 

 dissolution, passing f2 but failing f1 [Dissolution / BCS / IVIVC]

hello all, in a dissolution comparison, I got f2>50, f1>15, and within batch CV<15%. I am befuddled, would appreciate any suggestion.
thanks
Ahmed
dshah
★★  

India/United Kingdom,
2021-12-29 11:28
(842 d 18:22 ago)

@ Ahikal
Posting: # 22719
Views: 1,506
 

 dissolution, passing f2 but failing f1

Hello Ahmed!
Could you provide details for %CV? it seems that the dissolution is having higher %SD apart from 1st time point. Kindly try to evaluate other methods like Bootstrap/MSD.
Regards,
Dshah
UA Flag
Activity
 Admin contact
22,988 posts in 4,825 threads, 1,654 registered users;
114 visitors (0 registered, 114 guests [including 4 identified bots]).
Forum time: 06:51 CEST (Europe/Vienna)

The whole purpose of education is
to turn mirrors into windows.    Sydney J. Harris

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5