Loky do ★ Egypt, 20211013 17:06 (1120 d 15:30 ago) Posting: # 22627 Views: 3,079 

Dears If I have a bioavailability study and want to compare its PK results with published data, is there any specific statistical test that could be used to prove there is no significant difference between both results? Thanks in advance Edit: Category changed; see also this post #1. [Helmut] 
Helmut ★★★ Vienna, Austria, 20211014 12:59 (1119 d 19:37 ago) @ Loky do Posting: # 22628 Views: 2,363 

Hi Loky do, ❝ If I have a bioavailability study and want to compare its PK results with published data, is there any specific statistical test that could be used to prove there is no significant difference between both results? If you have the subject’s data of the previous study, you could work with logtransformed values and use a paired ttest. If not, i.e., you have only the mean (\(\small{\mu}\)), you could use a onesample ttest, where \(\small{t=\frac{\overline{x}\mu}{s/\sqrt{n}}}\) with \(\small{df=n1}\). Example in :
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Loky do ★ Egypt, 20211018 11:59 (1115 d 20:37 ago) @ Helmut Posting: # 22633 Views: 2,392 

Thanks, Dear Helmut 