Loky do ★ Egypt, 2021-10-13 17:06 (1120 d 15:30 ago) Posting: # 22627 Views: 3,079 |
|
Dears If I have a bioavailability study and want to compare its PK results with published data, is there any specific statistical test that could be used to prove there is no significant difference between both results? Thanks in advance Edit: Category changed; see also this post #1. [Helmut] |
Helmut ★★★ Vienna, Austria, 2021-10-14 12:59 (1119 d 19:37 ago) @ Loky do Posting: # 22628 Views: 2,363 |
|
Hi Loky do, ❝ If I have a bioavailability study and want to compare its PK results with published data, is there any specific statistical test that could be used to prove there is no significant difference between both results? If you have the subject’s data of the previous study, you could work with log-transformed values and use a paired t-test. If not, i.e., you have only the mean (\(\small{\mu}\)), you could use a one-sample t-test, where \(\small{t=\frac{\overline{x}-\mu}{s/\sqrt{n}}}\) with \(\small{df=n-1}\). Example in :
Problems:
— Dif-tor heh smusma 🖖🏼 Довге життя Україна! Helmut Schütz The quality of responses received is directly proportional to the quality of the question asked. 🚮 Science Quotes |
Loky do ★ Egypt, 2021-10-18 11:59 (1115 d 20:37 ago) @ Helmut Posting: # 22633 Views: 2,392 |
|
Thanks, Dear Helmut |