Sridhar.E
☆    

India,
2021-07-13 13:04
(1016 d 14:48 ago)

Posting: # 22468
Views: 1,976
 

 statistical approaches for dose-finding PK studies [Regulatives / Guidelines]

Post reply
Any one please help statistical approaches for dose-finding PK studies. How can i conclude or select the dose which having the high efficacy.
 
msmnainar
★    

India,
2021-07-17 21:04
(1012 d 06:48 ago)

@ Sridhar.E
Posting: # 22476
Views: 1,459
 

 statistical approaches for dose-finding PK studies

Post reply
Hi,

Not able to understand meaning of high efficacy here.

If you follow the sentinel dosing in your study design, you can conclude the dose based on PK and PD correlation.
—
Sundar. M
 
UA Flag
Activity
 Admin contact
22,993 posts in 4,828 threads, 1,656 registered users;
112 visitors (1 registered, 111 guests [including 3 identified bots]).
Forum time: 03:52 CEST (Europe/Vienna)

Never never never never use Excel.
Not even for calculation of arithmetic means.    Martin Wolfsegger

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5