VijithRoy
☆    

India,
2021-03-03 09:35
(1176 d 09:50 ago)

Posting: # 22239
Views: 2,435
 

 Confidence interval for PK and PD analysis [General Sta­tis­tics]

Hello everyone,

Why do we set 95% CI for PD data analysis and 90% CI for PK analysis.? Why not 90% CI for PD data analysis?

Please kindly clarify me and correct me if am wrong anywhere.


Edit: Category changed; see also this post #1[Helmut]

With Best Regards,
Vroy.
ElMaestro
★★★

Denmark,
2021-03-03 12:15
(1176 d 07:09 ago)

@ VijithRoy
Posting: # 22240
Views: 1,912
 

 Confidence interval for PK and PD analysis

Hello VijithRoy,

❝ Why do we set 95% CI for PD data analysis and 90% CI for PK analysis.? Why not 90% CI for PD data analysis?


can you please be much more specific?
There are lots of 90% CI's used in PD, so in order to get towards an answer for your question can you please give a lot more context including: Where do you submit the dossier, what drug is it, what is your endpoint, did you get sc.advice or do a controlled correspondence with the authority etc?

Pass or fail!
ElMaestro
VijithRoy
☆    

India,
2021-03-04 11:03
(1175 d 08:22 ago)

@ ElMaestro
Posting: # 22241
Views: 1,841
 

 Confidence interval for PK and PD analysis

❝ There are lots of 90% CI's used in PD, so in order to get towards an answer for your question can you please give a lot more context including: Where do you submit the dossier, what drug is it, what is your endpoint, did you get sc.advice or do a controlled correspondence with the authority etc?


Dear ElMaestro,

I was assuming that 95% CI uses for PD and 90% CI for PK analysis.
So setting up the CI depends upon our Statistical Modeling?


Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5[Helmut]

With Best Regards,
Vroy.
UA Flag
Activity
 Admin contact
23,035 posts in 4,835 threads, 1,643 registered users;
22 visitors (0 registered, 22 guests [including 7 identified bots]).
Forum time: 20:25 CEST (Europe/Vienna)

Satisfaction of one’s curiosity is one of the greatest sources
of happiness in life.    Linus Pauling

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5