VijithRoy
☆    

India,
2021-03-03 08:35
(48 d 11:07 ago)

Posting: # 22239
Views: 592
 

 Confidence interval for PK and PD analysis [General Sta­tis­tics]

Hello everyone,

Why do we set 95% CI for PD data analysis and 90% CI for PK analysis.? Why not 90% CI for PD data analysis?

Please kindly clarify me and correct me if am wrong anywhere.


Edit: Category changed; see also this post #1[Helmut]

With Best Regards,
Vroy.
ElMaestro
★★★

Denmark,
2021-03-03 11:15
(48 d 08:26 ago)

@ VijithRoy
Posting: # 22240
Views: 466
 

 Confidence interval for PK and PD analysis

Hello VijithRoy,




» Why do we set 95% CI for PD data analysis and 90% CI for PK analysis.? Why not 90% CI for PD data analysis?

can you please be much more specific?
There are lots of 90% CI's used in PD, so in order to get towards an answer for your question can you please give a lot more context including: Where do you submit the dossier, what drug is it, what is your endpoint, did you get sc.advice or do a controlled correspondence with the authority etc?

Pass or fail!
ElMaestro
VijithRoy
☆    

India,
2021-03-04 10:03
(47 d 09:39 ago)

@ ElMaestro
Posting: # 22241
Views: 413
 

 Confidence interval for PK and PD analysis

» There are lots of 90% CI's used in PD, so in order to get towards an answer for your question can you please give a lot more context including: Where do you submit the dossier, what drug is it, what is your endpoint, did you get sc.advice or do a controlled correspondence with the authority etc?

Dear ElMaestro,

I was assuming that 95% CI uses for PD and 90% CI for PK analysis.
So setting up the CI depends upon our Statistical Modeling?


Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5[Helmut]

With Best Regards,
Vroy.
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