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begoña ☆ Spain, 2020-10-08 14:14 (897 d 10:49 ago) Posting: # 21976 Views: 2,276 |
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I am trying to find information about BCS classification of Dexthrometorphan BrH Thank you |
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Sridhar.E ☆ India, 2020-10-08 14:27 (897 d 10:36 ago) @ begoña Posting: # 21978 Views: 1,999 |
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❝ I am trying to find information about BCS classification of Dexthrometorphan BrH Hai Dextromethorphan hydrobromide belongs to the class II of biopharmaceutics classification system (BCS), exhibits low solubility and high permeability. |
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begoña ☆ Spain, 2020-10-08 14:35 (897 d 10:28 ago) @ Sridhar.E Posting: # 21979 Views: 2,013 |
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❝ Dextromethorphan hydrobromide belongs to the class II of biopharmaceutics classification system (BCS), exhibits low solubility and high permeability. Thanks I read papers where it has classified as Class II, but also I found several publications that describe Dextromehorphan HBr as very high soluble substance. I was wondering if I could ask for a biowaiver, during the evaluation of an oral product containig dexthrometorphan. Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5! [Helmut] |
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Sridhar.E ☆ India, 2020-10-08 14:59 (897 d 10:04 ago) @ begoña Posting: # 21981 Views: 1,984 |
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❝ I read papers where it has classified as Class II, but also I found several publications that describe Dextromehorphan HBr as very high soluble substance. I gone through reviews, I found Dextromehorphan Practically insoluble in water. The Waiver request of in-vivo testing: 30 mg/600 mg based on acceptable bioequivalence studies on the 60 mg/1200 strength, acceptable dissolution testing across all strengths. Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5! [Ohlbe] |
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Helmut ★★★   Vienna, Austria, 2020-10-08 14:54 (897 d 10:09 ago) @ begoña Posting: # 21980 Views: 2,003 |
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Hi begoña, ❝ I am trying to find information about BCS classification of Dexthrometorphan BrH doi:10.14499/indonesianjpharm25iss3pp181 https://etd.ohiolink.edu/!etd.send_file?accession=mco1470340367&disposition=attachment — Dif-tor heh smusma 🖖🏼 Довге життя Україна! ![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png) Helmut Schütz ![[image]](https://static.bebac.at/img/CC by.png) The quality of responses received is directly proportional to the quality of the question asked. 🚮 Science Quotes |
Ing. Helmut Schütz