jabriges ☆ US, 20200624 17:46 (317 d 01:14 ago) Posting: # 21577 Views: 1,649 

I have a question about getting subject level random effect. The call of lme() in lme_lm.mod.r uses random=~drug  1subj I'm not seeing how this gives you a random effect for each subject. I understand the 1 removes the intercept, but doesn't the inclusion of drug there make the random effect differ by formulation, and hence period (for the same subject)?Any insight appreciated. Jay 
ElMaestro ★★★ Denmark, 20200625 07:40 (316 d 11:20 ago) @ jabriges Posting: # 21578 Views: 1,246 

Hi all, » random=~drug  1subj I do not offer an answer to the question at all, only I wish to say that I have no ideas, generally, how syntactically R works for lme and lmer when specifying random effects. All the stuff that involves "~", "" for random effects is entirely obscure to me, and I tried to read the various online resources for it, and help files for packages. I even ordered the book by Pinheiro & Bates to learn from it, but that book assumes that the reader knows everything there is to about mixed models and R syntax before you open it on page 1. It is also not clear to me how covariance matrix structures are actually set using the R functions. So, I think the question you asked jabriges is also highly relevant for me in a very general sense. I hope someone will chime in an educate me about the syntax. — Pass or fail! ElMaestro 
jabriges ☆ US, 20200625 16:12 (316 d 02:49 ago) @ ElMaestro Posting: # 21579 Views: 1,223 

Hi, Maestro. » So, I think the question you asked jabriges is also highly relevant for me in a very general sense. I hope someone will chime in an educate me about the syntax. There are places that you can read about R's formula syntax in general, like here. My question is specifically about the formula for random (see my OP) which seems to make the random coefficient a slope on the drug term, rather than a random intercept term (grouped by subject, of course), which was my understanding of the intended model. Jay 