abhimanyu ☆ Banglore, 20190813 15:11 (1141 d 00:13 ago) Posting: # 20494 Views: 2,069 

Hello Helmut/All, I have question regarding outlier test (Using Lund's method) for reference replicate crossover study design. How can we find outlier? which one will be appropriate scenario for any regulatory point of view? Scenario 1 : can we use test and individual reference (R R) to calculate standardized residual? Scenario 2 : Can we use test and average of reference (average of R R) to calculate standardized residual? Thanks in advance! — Abhimanyu 
ElMaestro ★★★ Denmark, 20190813 15:28 (1140 d 23:56 ago) @ abhimanyu Posting: # 20495 Views: 1,762 

Hi Abhimanyu, » I have question regarding outlier test (Using Lund's method) for reference replicate crossover study design. Sounds like a bad idea. » How can we find outlier? which one will be appropriate scenario for any regulatory point of view? The trick is to avoid generating outliers. In my small universe, there is no problem that merits a solution involving identification and and removal of outliers. — Pass or fail! ElMaestro 
Helmut ★★★ Vienna, Austria, 20190813 16:40 (1140 d 22:43 ago) @ abhimanyu Posting: # 20496 Views: 1,753 

Hi Abhimanyu, first of all I agree with ElMaestro. » How can we find outlier? which one will be appropriate scenario for any regulatory point of view?
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