abhimanyu ☆ Banglore, 20190813 17:11 (1504 d 23:46 ago) Posting: # 20494 Views: 2,174 

Hello Helmut/All, I have question regarding outlier test (Using Lund's method) for reference replicate crossover study design. How can we find outlier? which one will be appropriate scenario for any regulatory point of view? Scenario 1 : can we use test and individual reference (R R) to calculate standardized residual? Scenario 2 : Can we use test and average of reference (average of R R) to calculate standardized residual? Thanks in advance! — Abhimanyu 
ElMaestro ★★★ Denmark, 20190813 17:28 (1504 d 23:29 ago) @ abhimanyu Posting: # 20495 Views: 1,848 

Hi Abhimanyu, ❝ I have question regarding outlier test (Using Lund's method) for reference replicate crossover study design. Sounds like a bad idea. ❝ How can we find outlier? which one will be appropriate scenario for any regulatory point of view? The trick is to avoid generating outliers. In my small universe, there is no problem that merits a solution involving identification and and removal of outliers. — Pass or fail! ElMaestro 
Helmut ★★★ Vienna, Austria, 20190813 18:40 (1504 d 22:16 ago) @ abhimanyu Posting: # 20496 Views: 1,845 

Hi Abhimanyu, first of all I agree with ElMaestro. ❝ How can we find outlier? which one will be appropriate scenario for any regulatory point of view?
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