Bioequivalence and Bioavailability Forum

libaiyi ★ China, 2019-04-09 09:15 (1988 d 08:55 ago) Posting: # 20134 Views: 3,538	Tmax in three treatment, three period, three sequence design [Nonparametrics] Post reply
	Dear all, I have a question about Wilcoxon signed rank test on Tmax. In a three treatment, three period, three sequece design (two test formulations and one reference formulation with the sequences as T1-R-T2, R-T2-T1, and T2-T1-R), can we use Wilcoxon signed rank test for Tmax? If not, what can we do to statistically evaluate Tmax? Thanks in advance! Best, Libaiyi

jag009
★★★

NJ,
2019-04-12 20:19
(1984 d 21:51 ago)

@ libaiyi
Posting: # 20154
Views: 2,816

Tmax in three treatment, three period, three sequence design

Post reply

Hi,

❝ I have a question about Wilcoxon signed rank test on Tmax. In a three treatment, three period, three sequece design (two test formulations and one reference formulation with the sequences as T1-R-T2, R-T2-T1, and T2-T1-R), can we use Wilcoxon signed rank test for Tmax? If not, what can we do to statistically evaluate Tmax?

Yes there are other tests. You can't really use Wil Test because it's for 2 treatment comparisons.

J

Helmut ★★★ Vienna, Austria, 2019-04-12 21:14 (1984 d 20:56 ago) @ jag009 Posting: # 20156 Views: 2,847	Going beyond two periods Post reply
	Hi John & Libaiyi, ❝ Yes there are other tests. See this extremely old post and Detlew’s reply. Reach for the stars, even if you have to stand on a cactus. Susan Longacre — Dif-tor heh smusma 🖖🏼 Довге життя Україна! Helmut Schütz The quality of responses received is directly proportional to the quality of the question asked. 🚮 Science Quotes

Tmax in three treatment, three period, three sequence design [Nonparametrics]

Tmax in three treatment, three period, three sequence design

Going beyond two periods