Bioequivalence and Bioavailability Forum 01:19 CET

Main page Policy/Terms of Use Abbreviations Latest Posts

 Log in |  Register |  Search

tshianza
Junior

South Africa,
2018-09-28 08:16
(edited by tshianza on 2018-09-28 09:12)

Posting: # 19335
Views: 657
 

 Error in bear [R for BE/BA]

Hi all

I have been getting the following error when running the bear program in R

error in lm.fit(x y offset = offset singular.ok = singular.ok ...) na/nan/inf in 'y'

And I'm unsure of how my data should be adjusted
yjlee168
Senior
avatar
Homepage
Kaohsiung, Taiwan,
2018-09-28 09:49
(edited by yjlee168 on 2018-09-28 10:32)

@ tshianza
Posting: # 19336
Views: 546
 

 Error in bear

Dear tshianza,

The error may occur when trying to include a value of '0' or any non numeric (character, such as 'BLQ', "BLOQ' or 'BLLOQ') to do linear regression for the terminal elimination rate constant (i.e., λz). So please look at your dataset and remove the rows with conc. = 0 or = 'non numeric' (except data point with the time = 0). Then it should work.

» And I'm unsure of how my data should be adjusted

All the best,
---Yung-jin Lee
bear v2.8.3-2:- created by Hsin-ya Lee & Yung-jin Lee
Kaohsiung, Taiwan http://pkpd.kmu.edu.tw/bear
Download link (updated) -> here
Activity
 Thread view
Bioequivalence and Bioavailability Forum |  Admin contact
19,154 posts in 4,080 threads, 1,308 registered users;
online 14 (0 registered, 14 guests [including 6 identified bots]).

One can show the following: given any rule, however “fundamental”
or “necessary” for science, there are always circumstances
when it is advisable not only to ignore the rule,
but to adopt its opposite.    Paul Feyerabend

The BIOEQUIVALENCE / BIOAVAILABILITY FORUM is hosted by
BEBAC Ing. Helmut Schütz
HTML5 RSS Feed