giang nidqc
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Vietnam,
2018-09-27 10:55
(2036 d 12:21 ago)

Posting: # 19329
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 Spiramycine [Bioanalytics]

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Dear all,
I've been looking for any guidance of BE study for spiramycine but have not found anything. I found some articles, some used microbiological assay, some used HPLC methods (detect all 3 components or only Spiramycine I). As spiramycine have 3 main components (I: 85%, II: 5%; III: 10%), all have therapeutic effect, what APIs do we need to measure: all of these components individually, or just Spiramycine I?
THanks in advance!
 
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