Ana Cristina
☆    

Brazil,
2018-02-23 00:07

Posting: # 18447
Views: 1,550
 

 Randomization Crossover Bioequivalence [R for BE/BA]

Dear All,

Could you please give me an advice for the software R use for subject randomization Balanced for sex?

Example: 72 subjects being:
36 for test medication and 36 for reference medication
of the 36 subjects on the test medication: 18 female and 18 male
of the 36 subjects of the reference medication: 18 female and 18 male

Thank you,

Ana Cristina Mazuqueli


Edit: Category changed; see also this post #1. [Helmut]
ElMaestro
★★★

Belgium?,
2018-02-23 06:20

@ Ana Cristina
Posting: # 18448
Views: 1,219
 

 Randomization Crossover Bioequivalence

Hi Ana Cristina,

» 36 for test medication and 36 for reference medication
» of the 36 subjects on the test medication: 18 female and 18 male
» of the 36 subjects of the reference medication: 18 female and 18 male

This can be done in R without too much coding.
But why is the title something with crossover when the description here is not suggestive of such a design? Was the 36+36 (or 18+18+18+18) only applicable for period 1?

I could be wrong, but...
Best regards,
ElMaestro
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