Bioequivalence and Bioavailability Forum • Incorrect MRT data export in "bear"

roman_max
☆

Russia,
2017-12-27 16:29
(2472 d 04:56 ago)

Posting: # 18103
Views: 5,302

Incorrect MRT data export in "bear" [🇷 for BE/BA]

Dear all,
surprisingly found that after NCA and stat.analysis there is an error in MRT data export for T and R - csv file contains the same data (it is wrong)

MRT0inf_Test   MRT0inf_Ref

4,61                 4,61

6,76                 6,76

5,49                 5,49

3,91                 3,91

2,38                 2,38

2,76                 2,76

2,79                 2,79

but in txt file they are different (it is right)

subj  Test    Ref  Ratio

   1 4.611  3.468 1.330

   2 6.757  3.794 1.781

   3 5.491 14.003 0.392

   4 3.908  3.074 1.271

   5 2.377  2.384 0.997

   6 2.755  2.948 0.935

   7 2.792  2.857 0.977

Has anyone faced with that? :confused:

yjlee168
★★★

Kaohsiung, Taiwan,
2017-12-27 19:17
(2472 d 02:08 ago)

@ roman_max
Posting: # 18104
Views: 4,449

Incorrect MRT data export in "bear"

Post reply

Hi roman_max,

Thanks for reporting the error. I will check the codes to see what it is going. It looks like MRT0inf_Ref does not point to the Ref. correctly (but to the Test) when generating csv file. Sorry about this error.

[edited] I've already fixed the error. It only occurs in MRT0inf_Ref. Thanks again.

—
All the best,
-- Yung-jin Lee
bear v2.9.1:- created by Hsin-ya Lee & Yung-jin Lee
Kaohsiung, Taiwan https://www.pkpd168.com/bear
Download link (updated) -> here

roman_max
☆

Russia,
2018-03-13 11:30
(2396 d 09:54 ago)

@ yjlee168
Posting: # 18527
Views: 3,974

Incorrect MRT data export in "bear"

Post reply

Dear yjlee168, sorry for my belate response. Today I`ve tried to check the issue with MRT and found that the problem still exist. I`ve run a different dataset and in outputs I have a different results - in ..._nca_pk.txt file (it seems right, at least they are different for T and R), but in ...misc_pk.csv MRT results for T and R are the same.
I`ve also re-installed the bear package from the lates zip file taken from sourceforge web-site. No changes in this matter, unfortunately.
Please re-check the code (or something else) to resolve this issue. Thank you.

yjlee168
★★★

Kaohsiung, Taiwan,
2018-03-13 12:15
(2396 d 09:10 ago)

@ roman_max
Posting: # 18528
Views: 3,901

Incorrect MRT data export in "bear"

Post reply

Dear roman_max,

Yes, you are right about this error. I have not released the update yet, though I have already fixed the error. The current version is still v2.8.3. You have to do it manually right now. Sorry about that I did not explain clear enough in last response.

—
All the best,
-- Yung-jin Lee
bear v2.9.1:- created by Hsin-ya Lee & Yung-jin Lee
Kaohsiung, Taiwan https://www.pkpd168.com/bear
Download link (updated) -> here