BE-proff
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2016-04-26 14:32
(3285 d 03:12 ago)

Posting: # 16241
Views: 4,396
 

 Splitting into groups vs variation [General Sta­tis­tics]

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Dear All,

Let's say I have 60 subjects that must be dosed according to BE-protocol.

My study site can accommodate only 15 subjects so that to dose all people I have to split them into several groups.

Does this splitting have an impact on variation of PK?

Should it be analyzed in ANOVA?
 
GSTATS
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India,
2016-04-29 15:11
(3282 d 02:33 ago)

@ BE-proff
Posting: # 16259
Views: 3,396
 

 Splitting into groups vs variation

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Dear BE-proff,

I do no think that it is always possible to get all subjects, required in study, dosed at the same time. It is not required to have group variable in ANOVA if these groups are made randomly and not based on any specific characteristic of subjects.

GSTATS

Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5! [Helmut]
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Let Noble Thoughts come from Every Side: RIG VEDA
 
mittyri
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Russia,
2016-04-30 22:48
(3280 d 18:56 ago)

@ BE-proff
Posting: # 16261
Views: 3,311
 

 Splitting into groups vs variation

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Dear BE-proff,

et quī quaerit, invenit...


1. http://forum.bebac.at/forum_entry.php?id=16137&page=1&order=time
2. http://forum.bebac.at/mix_entry.php?id=10424#p13416
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Kind regards,
Mittyri
 
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