krishnamurthy ca
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2007-04-21 13:40
(6983 d 13:34 ago)

Posting: # 683
Views: 6,855
 

 MRM values in LCMS [Bioanalytics]

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Dear all

This is regarding the parameters Q1 and Q3 mass (amu). I would like to know how much variation is acceptable from the set value. For example if Q1 is found to be 413.2C for a molecule during method validation, can it vary between 412.7 to 413.7C during subject analysis. (+5).

Pl also comment if any other parameters (like CUR, CAD, IS, TEM etc) needs to be controlled as part of MRM settings.

Regards
Krishnamurthy
 
Helmut
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2007-04-22 23:01
(6982 d 04:13 ago)

@ krishnamurthy ca
Posting: # 685
Views: 5,364
 

 MRM values in LCMS

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Dear Krishnamurthy!

Oh, this very a very tricky question.
Please condsider posting in the Chromatography Forum also.
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