eduardojmorales
●    

2006-09-29 22:28
(7187 d 04:01 ago)

Posting: # 262
Views: 9,675
 

 Costs question [Bioanalytics]

The HPLC analysis of one sample costs around $100 in El Salvador, Central America. The average BE study has 1200 samples. That means $120,000 in chemical analysis alone. How does a BE lab charge $65,000 for the study of Carvedilol in Mass spectrophotometer?
Helmut
★★★
avatar
Homepage
Vienna, Austria,
2006-09-30 14:03
(7186 d 12:26 ago)

@ eduardojmorales
Posting: # 263
Views: 7,682
 

 Costs question

Dear Eduardo!

❝ The HPLC analysis of one sample costs around $100 in El Salvador, Central

❝ America. The average BE study has 1200 samples. That means $120,000 in

❝ chemical analysis alone.


IMHO $100 for an HPLC sample is just ridiculous!
In Europe I would consider $20 - $40 (calculated on an exchange rate of EUR->USD of 1.25) per sample in a GLP-certified lab reasonable (depending on the method)...

❝ How does a BE lab charge $65,000 for the study of

❝ Carvedilol in Mass spectrophotometer?


Why not? This means $54/sample, which is not unrealistic; I know some MS-labs calculating prices as low as $45/sample (including method development and validation).
Maybe you should consider changing your CRO - or at least ship the samples for analysis to a more economically priced site... ;-)

Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
eduardojmorales
●    

2006-10-02 22:33
(7184 d 03:56 ago)

@ Helmut
Posting: # 264
Views: 7,617
 

 Costs question

Thank you Helmut:
It was avery nice of you to answer so promptly. Do you have names for these CROs? I would like to investigate more on this subject.
:-) Thanks in advance!
Helmut
★★★
avatar
Homepage
Vienna, Austria,
2006-10-02 22:46
(7184 d 03:43 ago)

@ eduardojmorales
Posting: # 265
Views: 7,586
 

 Costs question

Dear Eduardo!

❝ Thank you Helmut:

❝ It was avery nice of you to answer so promptly.


You are welcome!

❝ Do you have names for these CROs?

❝ I would like to investigate more on this subject.


Yes, but since the forum is noncommercial in nature, I will not publish the name of CROs in the forum...
If you have specific questions, you may contact me through my website.

Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
UA Flag
Activity
 Admin contact
23,653 posts in 4,991 threads, 1,571 registered users;
345 visitors (0 registered, 345 guests [including 47 identified bots]).
Forum time: 02:30 CEST (Europe/Vienna)

I’m all in favor of the democratic principle
that one idiot is as good as one genius, but I draw the line
when someone takes the next step and concludes
that two idiots are better than one genius.    Leo Szilard

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5