Tina
★    

India,
2014-04-25 12:17
(4051 d 12:21 ago)

Posting: # 12894
Views: 6,441
 

 LLOQ and BLQ terminologies [Bioanalytics]

Dear all,

Can LLOQ and BLQ terminologies be used interchangeably? Some CROs are using LLOQ while others are using BLQ? What would be the EU and FDA's referred terminologies?

Kind regards,
Tina.


Edit: Category changed. [Helmut]
Helmut
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Vienna, Austria,
2014-04-25 13:28
(4051 d 11:10 ago)

@ Tina
Posting: # 12895
Views: 5,791
 

 LLOQ ≠ BLQ

Hi Tina,

❝ Can LLOQ and BLQ terminologies be used interchangeably?


That’s not a question of terminology, but rather of apples and oranges.
LLOQ: (Lower) Limit of Quantification
BLQ:   Below the (Lower) Limit of Quantification

Example: If the LLOQ is 10 ng/mL, any back-calculated value <10 ng/mL should not be reported as a numeric value, but with the character-string “BLQ” instead.

In the future maybe the list of commonly used Abbreviations (linked on top of the page) will help.

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Tina
★    

India,
2014-04-25 13:43
(4051 d 10:55 ago)

@ Helmut
Posting: # 12896
Views: 5,584
 

 LLOQ ≠ BLQ

Dear Helmut,

Thanks for the clarification.

Kind regards,
Tina.
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