PTM139
☆    

India,
2012-05-03 07:58
(5162 d 18:04 ago)

Posting: # 8495
Views: 3,509
 

 Partial replicate design [Design Issues]

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Do you anticipate any impact of changing the study design from partial replicate design (for pilot BE) to crossover design (for pivotal BE) on the results?

Edit: Please follow the Policy. [Helmut]
 
Dr_Dan
★★  

Germany,
2012-05-03 17:17
(5162 d 08:45 ago)

@ PTM139
Posting: # 8502
Views: 2,785
 

 Partial replicate design

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Dear PTM139
A partial replicate design for a pilot study does IMHO not make much sense. For a pivotal study you can change from a cross-over to a replicate design if you observe a high ANOVA CV% in the pilot study.
Kind regards
Dan
—
Kind regards and have a nice day
Dr_Dan
 
PTM139
☆    

India,
2012-05-03 18:38
(5162 d 07:24 ago)

@ Dr_Dan
Posting: # 8506
Views: 2,806
 

 Partial replicate design

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Dear Dr Dan,

Thank you for the reply.

Edit: Full quote removed. Please delete anything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Helmut]
 
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