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Phaneendra.K ☆ 2010-12-31 15:54 (5655 d 06:34 ago) Posting: # 6365 Views: 4,261 |
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Dear all, What is the reason behind giving 240 ml of water only, after administering the IP? How is this justified. — Thanks and Regards, PK |
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Helmut ★★★   Vienna, Austria, 2010-12-31 16:55 (5655 d 05:33 ago) @ Phaneendra.K Posting: # 6369 Views: 3,635 |
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Dear Phani! ❝ What is the reason behind giving 240 ml of water only, after administering the IP? Convention - which differs between countries. See this thread and please search the forum in the future. ❝ How is this justified. Was never justified, IMHO. One urban myth is that the volume is related to 250 mL used in the BCS. But: the stomach is never ‘dry’ - contains about 500 mL liquid in the fasted state, and water has a very short half-life… Actually it should guarantee proper swallowing (with too little fluid the formulation may stick to the oesophagus). — Dif-tor heh smusma 🖖🏼 Довге життя Україна! ![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png) Helmut Schütz ![[image]](https://static.bebac.at/img/CC by.png) The quality of responses received is directly proportional to the quality of the question asked. 🚮 Science Quotes |
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Ohlbe ★★★ France, 2010-12-31 17:02 (5655 d 05:26 ago) @ Helmut Posting: # 6371 Views: 3,633 |
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Dear both, ❝ Was never justified, IMHO. Remember this recommendation comes from the US. 240 ml = 8 US fluid ounces = 1/2 US pint. Just the regular size of a US glass of water, it seems. Regards Ohlbe — Regards Ohlbe |
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Helmut ★★★ Vienna, Austria, 2010-12-31 17:47 (5655 d 04:41 ago) @ Ohlbe Posting: # 6374 Views: 3,599 |
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Dear Ohlbe! ❝ ❝ Was never justified, IMHO. ❝ ❝ Remember this recommendation comes from the US. 240 ml = 8 US fluid ounces = 1/2 US pint. Just the regular size of a US glass of water, it seems. Yes, right - but I would not call that the justification Phani asked for…  Forgot to link this post. — Dif-tor heh smusma 🖖🏼 Довге життя Україна! Helmut Schütz The quality of responses received is directly proportional to the quality of the question asked. 🚮 Science Quotes |
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Phaneendra.K ☆ 2011-01-02 10:29 (5653 d 11:59 ago) @ Helmut Posting: # 6381 Views: 3,516 |
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❝ Was never justified, IMHO. Dear HS, Hi, What is IMHO you write in many replies Edit: Full quote removed. Please delete anything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Helmut] — Thanks and Regards, PK |
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Helmut ★★★ Vienna, Austria, 2011-01-02 15:46 (5653 d 06:42 ago) @ Phaneendra.K Posting: # 6383 Views: 3,612 |
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Dear Phani! In the future please delete anything from the text of the original poster which is not necessary in understanding your answer; see also this post and the Forum’s Policy! ❝ Hi, What is IMHO you write in many replies  comes up with 14+ mio hits.What about this one? — Dif-tor heh smusma 🖖🏼 Довге життя Україна! Helmut Schütz The quality of responses received is directly proportional to the quality of the question asked. 🚮 Science Quotes |
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manan ☆ Ahmedabad, 2011-01-01 07:19 (5654 d 15:09 ago) @ Phaneendra.K Posting: # 6377 Views: 3,546 |
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Dear Phani Different guidances suggests different volume of water. i guess the basic funda is for easy swallowing of the IMP |
Ing. Helmut Schütz