MaggieSantos
☆    

Portugal,
2013-05-30 22:53
(4776 d 20:57 ago)

Posting: # 10689
Views: 4,749
 

 Ezetimibe plus simvastatin [Design Issues]

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Dear all,

What are your opinion on the best sample size for a 2*2 crossover design of a bioequivalence study for ezetimibe/simvastatin formulations.
I need some suggestions and rationale.


Best Regards

MS
 
Dr_Dan
★★  

Germany,
2013-05-31 13:13
(4776 d 06:38 ago)

@ MaggieSantos
Posting: # 10692
Views: 4,191
 

 Ezetimibe plus simvastatin

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Dear Maggie
I hope this helps
Migoya EM; Bergman A; Hreniuk D et al.: Bioequivalence of an ezetimibe/simvastatin combination tablet and coadministration of ezetimibe and simvastatin as separate tablets in healthy subjects. Int J Clin Pharmacol Ther 2006 Feb;44(2):83-92
Kind regards
Dan
—
Kind regards and have a nice day
Dr_Dan
 
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