ramgopi
☆    

India,
2009-02-19 08:16
(6341 d 04:49 ago)

Posting: # 3275
Views: 2,372
 

 Addition of fragment ions for quantitation [Regulatives / Guidelines]

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Dear all :-),

Greetings, for a preclinical study we are working in addition of fragments for quantitation in LCMSMS, is it acceptable by the regulatory authorities? kindly give me a suggestion.

Thanks and Regards

R.Gopinath
 
babun14
☆    

2009-03-04 08:21
(6328 d 04:44 ago)

(edited on 2009-03-04 10:14)
@ ramgopi
Posting: # 3311
Views: 1,761
 

 Addition of fragment ions for quantitation

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Hello Gopi,


We did increase the response of analyte by adding more fragment for quantitation for regulatory study and I believe it should not be a problem as long as your method is validated .

Thanks

Bani

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Edit: Full quote removed. Please see this post! [Ohlbe]
 
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