rajasekhar
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India,
2017-01-07 08:04
(3460 d 02:32 ago)

Posting: # 16938
Views: 5,206
 

 Replicate designs [RSABE / ABEL]

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I am looking for a reference to on what basis we are doing partially and fully replicate studies for high variable drugs (i.e. CV more than 30 %).

My doubt is suppose the drug having the CV is 45%, then how can we decide whether we need to go 3 way or 4 way

Edit: Category changed; see also this post #1. [Helmut]
 
nobody
nothing

2017-01-07 21:41
(3459 d 12:55 ago)

@ rajasekhar
Posting: # 16940
Views: 4,139
 

 Replicate designs

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Hi!
I read somewhere that when the number "45" comes into play you definitely have to go 5.5 periods and sequences. Or something like this. Not really sure...
—
Kindest regards, nobody
 
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