Dr_Dan ★★ Germany, 2010-12-10 15:15 (5253 d 00:30 ago) Posting: # 6289 Views: 5,393 |
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Dear Yung-jin and all others I just installed BEAR 2.5.3 and tried to get used to it by recalculating a BE study: 18 subjects included, 17 completed the study, so the data set is inbalanced. When I look at the results in the files Statistical_summaries.txt and ANOVA_stat.txt I realized that there is a discrepancy: Statistical_summaries.txt: Parameters F values P vales PE (%) lower 90%CI upper 90%CI ANOVA_stat.txt: Cmax 97.334 91.641 103.382 The calculation was performed at the same time using the same data set. Could you please explain why? I would have expected that they should be exactly the same. What is the reason for presenting different point estimators and confidence intervals? I am looking forward to your reply Kind regards Dan — Kind regards and have a nice day Dr_Dan |
yjlee168 ★★★ ![]() ![]() Kaohsiung, Taiwan, 2010-12-10 20:51 (5252 d 18:54 ago) (edited on 2010-12-10 23:39) @ Dr_Dan Posting: # 6291 Views: 4,319 |
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Dear Dr. Dan, I think that you just found a bug in bear with imbalanced dataset of a 2x2 crossover. It only happens to imbalanced dataset. The test dataset that I used was a balanced dataset. Thus, it has not been found or reported before. I will fix the bug soon. Sorry about this and thank you for your feedback. --- [Edit]: I've already fixed the error now (I think) and will test it with more data later. — All the best, -- Yung-jin Lee bear v2.9.2:- created by Hsin-ya Lee & Yung-jin Lee Kaohsiung, Taiwan https://www.pkpd168.com/bear Download link (updated) -> here |