Bioequivalence and Bioavailability Forum • Randomization Crossover Bioequivalence

Ana Cristina
☆

Brazil,
2018-02-23 01:07
(2673 d 19:16 ago)

Posting: # 18447
Views: 3,919

Randomization Crossover Bioequivalence [🇷 for BE/BA]

Dear All,

Could you please give me an advice for the software R use for subject randomization Balanced for sex?

Example: 72 subjects being:
36 for test medication and 36 for reference medication
of the 36 subjects on the test medication: 18 female and 18 male
of the 36 subjects of the reference medication: 18 female and 18 male

Thank you,

Ana Cristina Mazuqueli

Edit: Category changed; see also this post #1. [Helmut]

ElMaestro
★★★

Denmark,
2018-02-23 07:20
(2673 d 13:02 ago)

@ Ana Cristina
Posting: # 18448
Views: 3,004

Randomization Crossover Bioequivalence

Post reply

Hi Ana Cristina,

❝ 36 for test medication and 36 for reference medication

❝ of the 36 subjects on the test medication: 18 female and 18 male

❝ of the 36 subjects of the reference medication: 18 female and 18 male

This can be done in R without too much coding.
But why is the title something with crossover when the description here is not suggestive of such a design? Was the 36+36 (or 18+18+18+18) only applicable for period 1?

—
Pass or fail!
ElMaestro