Bioequivalence and Bioavailability Forum • R-Software for Williams’ Design

Ken Peh
★

Malaysia,
2014-03-18 14:05
(4111 d 04:52 ago)

Posting: # 12652
Views: 4,349

R-Software for Williams’ Design [🇷 for BE/BA]

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Dear Members,

Appreciate if could have your feedback on the following questions.

May I know if there is any software in R that can handle Williams’ design ?
Can Bear be used for 3x3x3 and 4x4x4 (or William Design) ? Any other software in R that can handle these study designs ?
Bear can analyze full replicate design, RTRT/TRTR. What about RTTR/TRRT or other sequence ?

Thank you.

Regards,
Ken

Edit: Category changed. [Helmut]

yjlee168
★★★

Kaohsiung, Taiwan,
2014-03-18 18:11
(4111 d 00:46 ago)

@ Ken Peh
Posting: # 12659
Views: 3,494

R-Software for Williams' Design

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Dear Ken,

❝ [...]

❝ 1. May I know if there is any software in R that can handle Williams’ design ?

Probably you should google this.

❝ 2. Can Bear be used for 3x3x3 and 4x4x4 (or William Design) ? Any other software in R that can handle these study designs ?

No, bear can only handle 2-treatment, 2-sequence, and 2-6 periods non-replicated or replicated crossover studies. Sorry about this.

❝ 3. Bear can analyze full replicate design, RTRT/TRTR. What about RTTR/TRRT or other sequence ?

RTTR/TRRT? yes, should be fine.

Hope this can help.

—
All the best,
-- Yung-jin Lee
bear v2.9.2:- created by Hsin-ya Lee & Yung-jin Lee
Kaohsiung, Taiwan https://www.pkpd168.com/bear
Download link (updated) -> here