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smk1976 ☆ India, 2007-12-30 20:47 (6338 d 18:46 ago) Posting: # 1441 Views: 4,834 |
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Dear HS, I have some data to do BA studies 1. Dose 150mg and route of Admin: Oral. 2. Drugs: 6 combinations of drugs were used. 3. The conc was found out between 0 to 4.5h and the time interval was 0.5h. 4. Is it possible to find out all the PK Parameters like Vd, T1/2, ect... using Winnonlin 2.1 or Kinetica 4.4 5. If so, please tell me how to do those things. i searched in the help files of both the softwares. not get the things. expecting your reply. if your answers is with some examples, it will be very much useful and understandable for me. since i am a beginner in this field. |
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SDavis ★★  UK, 2008-11-18 18:04 (6014 d 21:28 ago) @ smk1976 Posting: # 2720 Views: 3,647 |
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Dear SMK, I noticed you were asking about Kinetica and WinNonlin and how to use them - I have used both these s/w and each have their advantages, however with such a general question I think starting with a training course and/or a text book would be a good start. I am now a trainer at Pharsight and would like to confirm the current version of WinNonlin is in fact 5.2.1 although you will see a new release, Version 6 - WinNonlin Phoenix in early 2009 that I think will be quite exciting. We have courses all around the world, and are listed at http://www.pharsight.com/training. Some 'local' meetings for the EMEA are; WinNonlin v5.2 Hands-on training: 2-3 Dec 2008 London, UK, WinNonlin at BIOAVAILABILITY, BIOEQUIVALENCE, PHARMACOKINETICS & BEYOND 1-3 Dec 2008 Ahmedabad, India WinNonlin v5.2 Hands-on training: 9-10 Dec 2008 Hyderabad WinNonlin v5.2 Hands-on: 24-25 Feb 2009 Berlin, Germany For Kinetica training you now have to contact ThermoFisher, I'm not sure of the best contact there anymore. Best regards, Simon. PS Sorry for the late reply - I only recently joined the forum. |
Ing. Helmut Schütz