joyjac
★    

Philippines,
2011-06-07 03:57
(5500 d 05:27 ago)

Posting: # 7081
Views: 13,433
 

 BCS for Phenylephrine [Dissolution / BCS / IVIVC]

Post reply
Can anyone share me the BCS of Phenylephrine (PE). While literature search indicate that PE is freely soluble in water, I can't find any information on the BCS of the said drug. Would appreciate it very much.

Thanks.
 
Helmut
★★★
avatar
Homepage
Vienna, Austria,
2011-06-07 04:42
(5500 d 04:42 ago)

@ joyjac
Posting: # 7082
Views: 11,824
 

 Class III?

Post reply
Dear Joy!

❝ While literature search indicate that PE is freely soluble in water, I can't find any information on the BCS of the said drug.


1. Yes 2. Me not either

I would guess it is in class III (like pseudoephedrine). In DrugBank you find estimated logPs of -0.69 and -0.10. For future searches, see also TSRL’s BCS database.
—
Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
 
UA Flag
Activity
 Admin contact
23,655 posts in 4,993 threads, 1,572 registered users;
347 visitors (0 registered, 347 guests [including 27 identified bots]).
Forum time: 09:24 CEST (Europe/Vienna)

The real struggle is not between the right and the left
but between the party of the thoughtful
and the party of the jerks.    Jimmy Wales

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5