joyjac
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Philippines,
2011-06-07 03:57
(5501 d 10:24 ago)

Posting: # 7081
Views: 13,439
 

 BCS for Phenylephrine [Dissolution / BCS / IVIVC]

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Can anyone share me the BCS of Phenylephrine (PE). While literature search indicate that PE is freely soluble in water, I can't find any information on the BCS of the said drug. Would appreciate it very much.

Thanks.
 
Helmut
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Vienna, Austria,
2011-06-07 04:42
(5501 d 09:39 ago)

@ joyjac
Posting: # 7082
Views: 11,830
 

 Class III?

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Dear Joy!

❝ While literature search indicate that PE is freely soluble in water, I can't find any information on the BCS of the said drug.


1. Yes 2. Me not either

I would guess it is in class III (like pseudoephedrine). In DrugBank you find estimated logPs of -0.69 and -0.10. For future searches, see also TSRL’s BCS database.
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