Bhupesh
☆    

India,
2008-05-28 12:08
(6601 d 11:38 ago)

Posting: # 1877
Views: 8,219
 

 dissolution media for Soft gelatin capsule [Dissolution / BCS / IVIVC]

Post reply
Hi everyone :-)
I am looking for some dissolution medias for Soft gelatin capsule products containing nonpolar and also for Soft gelatin capsule products containing polar excipients
Please help me out
Regards
 
H_Rotter
★    

Germany,
2008-06-06 13:40
(6592 d 10:06 ago)

@ Bhupesh
Posting: # 1926
Views: 6,550
 

 Potential references

Post reply
Hi Bhupesh,

consider searching Vivian Gray's 'Dissolution Technologies'; articles are available online.

Regards,
Hermann
 
John Gray
●    

2008-06-23 09:42
(6575 d 14:03 ago)

@ Bhupesh
Posting: # 1964
Views: 6,594
 

 dissolution media for Soft gelatin capsule

Post reply
Actually what is the problem with FDA recommended biorelevant medias 1.2, 4.5, 6.8
 
Bhupesh
☆    

India,
2008-07-09 10:02
(6559 d 13:43 ago)

@ John Gray
Posting: # 2008
Views: 6,674
 

 dissolution media for Soft gelatin capsule

Post reply
Hello John
The main problem is that we are not getting any differentiating and there is difference in both the formulation reference having insoluble content in it and test sample has water soluble content.
 
UA Flag
Activity
 Admin contact
23,655 posts in 4,993 threads, 1,570 registered users;
236 visitors (0 registered, 236 guests [including 141 identified bots]).
Forum time: 23:46 CEST (Europe/Vienna)

Scientists often have a naïve faith that
if only they could discover enough facts about a problem,
these facts would somehow arrange themselves
in a compelling and true solution.    Theodosius Dobzhansky

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5