saimsc007
☆    

India,
2012-05-02 13:46
(5161 d 19:01 ago)

Posting: # 8488
Views: 5,112
 

 Inter Subject Variability [Power / Sample Size]

Dear All,

Can you please let me know the formula for Inter subject variability in SAS/Statistics


Edit: Category changed. [Helmut]
Helmut
★★★
avatar
Homepage
Vienna, Austria,
2012-05-02 15:09
(5161 d 17:38 ago)

@ saimsc007
Posting: # 8489
Views: 4,304
 

 What for?

Dear saimsc!

❝ Can you please let me know the formula for Inter subject variability in SAS/Statistics


See here. Counter question: What for do you need CVinter (between subjects)? In sample size estimations you need CVtotal (parallel groups) or CVintra (cross-over studies - within subjects); CVinter is irrelevant in any case.

Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
saimsc007
☆    

India,
2012-05-02 15:22
(5161 d 17:25 ago)

@ Helmut
Posting: # 8490
Views: 4,234
 

 What for?

Thanks for the post!!!

I got it... and we are presenting both the inter and intra subject variability values in ANVISA report.


Edit: Full quote removed. Please delete anything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Ohlbe]
Helmut
★★★
avatar
Homepage
Vienna, Austria,
2012-05-02 16:57
(5161 d 15:50 ago)

@ saimsc007
Posting: # 8491
Views: 4,377
 

 ANVISA…

Dear saimsc!

❝ […] we are presenting both the inter and intra subject variability values in ANVISA report.


Well, cough, ANVISA… :-D

Just for completeness: EMA (2011) requires the CV calculated from residual mean squares (i.e., CVintra for cross-overs, CVtotal for parallel groups, CVWR for replicate studies).

Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
UA Flag
Activity
 Admin contact
23,655 posts in 4,993 threads, 1,570 registered users;
124 visitors (0 registered, 124 guests [including 14 identified bots]).
Forum time: 08:47 CEST (Europe/Vienna)

I have finally come to the konklusion
that a good reliable set ov bowels
iz worth more to a man
than enny quantity of brains.    Josh Billings

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5