Bioequivalence and Bioavailability Forum

Subject	Author	Posted	Rep.	last R.	Views
statistical test for Bioavailability studies One-sample t-test One-sample t-test	Loky do	2021-10-13 15:06	2	2021-10-18 07:59	1,498
Randomization 2:1 allocation 2:1 allocation	msmnainar	2021-06-22 14:24	2	2021-06-23 14:49	1,446
DDSolver Issue DDSolver Issue DDSolver Issue DDSolver Issue DDSolver Issue	Laszlo Istvan Orosz	2021-06-09 14:12	4	2021-06-11 07:51	1,646
higher order crossover methodology All dosed subjects have to be analyzed All dosed subjects have to be analyzed All dosed subjects have to be analyzed All dosed subjects have to be analyzed higher order crossover methodology higher order crossover methodology higher order crossover methodology Fed (IBD) → fasting Fed (IBD) → fasting	sweiner	2020-06-30 01:07	9	2021-03-16 15:00	6,760
Degrees of freedom DF in higher-order Xover (again) Degrees of freedom	Mikkabel	2021-03-04 17:20	2	2021-03-04 21:23	1,753
Confidence interval for PK and PD analysis Confidence interval for PK and PD analysis Confidence interval for PK and PD analysis	VijithRoy	2021-03-03 08:35	2	2021-03-04 09:03	1,722
Group Effect Single site?	alghazam	2021-01-18 22:32	1	2021-01-19 10:32	1,722
Intra Subject Variability CVintra in replicate designs (→ 2 IBDs) Intra Subject Variability	clinicalservices	2021-01-05 08:19	2	2021-01-05 23:11	1,690
Significant effects Significant effects: Don’t worry, be happy! Significant effects: Don’t worry, be happy!	Moloko	2020-12-22 11:41	2	2020-12-23 12:24	1,723
statistical calculation procedures for 4 arm studies 4 periods (BE fed & fasting)	Loky do	2020-10-12 23:38	1	2020-10-12 21:58	1,246
Randomization Sequences in fully replicate williams’ design Tricky Tricky Tricky Tricky Very tricky	Researcher101	2020-10-10 19:27	5	2020-10-11 08:57	1,761
Treatment effect justification Treatment effect justification statistically significant ≠ clinically relevant statistically significant ≠ clinically relevant Problems with low variability	Sivakrishna	2020-10-07 08:15	4	2020-10-09 13:04	2,174
Adjusted indirect comparisons: Algebra Adjusted indirect comparisons: Algebra Adjusted indirect comparisons: Typo SE of ∆? SE of ∆? or what? SE of ∆ SE of ∆	Helmut	2020-10-01 16:41	6	2020-10-04 08:23	2,029
Decision of confidence interval of three period BE study Two tests and one reference Two tests and one reference Two tests and one reference Two regions: No α adjustment Two regions: No α adjustment Two regions: different populations Decision of confidence interval of three period BE study Any of two tests and one reference Any of two tests and one reference Hey wait a moment.... Hey wait a moment.... Pilot or pivotal ? Pilot or pivotal ? Pilot or pivotal ? Pilot or pivotal ? Pilot or pivotal ? Pilot or pivotal ? Pilot or pivotal ? Pilot or pivotal ? Pilot or pivotal ? Hey, hey wait another moment.... Hey, hey wait another moment.... Old belives die hard	libaiyi	2018-06-26 12:00	23	2020-08-31 09:26	13,992
EMA dataset I, can someone post results? EMA dataset I, can someone post results? EMA dataset I, can someone post results? EMA dataset I (PHX/WNL 8.1) EMA dataset I (PHX/WNL 8.1) EMA dataset I (PHX/WNL 8.1) EMA dataset I (PHX/WNL 8.1)	ElMaestro	2020-08-14 20:54	6	2020-08-19 23:05	3,094