Bioequivalence and Bioavailability Forum

Subject	Author	Posted	Rep.	last R.	Views
Different power of AUC vs. Cmax at stage I - continuation rules Different power of AUC vs. Cmax at stage I - continuation rules Different power of AUC vs. Cmax at stage I - continuation rules AUC vs. Cmax Assumption	Nisha	2015-09-17 13:28	4	2015-09-17 22:15	7,671
Does unequal alpha distribution make sense? Maybe; but watch the TIE! Advantages Advantages Advantages – performance measure Advantages – performance measure Advantages – performance measure Advantages – performance measure Histogram wonder Histogram charlatanry Histogram beauty Histogram beast Does unequal alpha distribution make sense? Does unequal alpha distribution make sense? Does unequal alpha distribution make sense? Old beliefs die hard Old beliefs die hard Old beliefs die hard Old beliefs die hard Old beliefs die hard ♩ ♪♫♬`·.¸¸.·´`·.¸¸. TSD only an option in exceptional cases TSD only an option in exceptional cases OT OT Banana splits	Dr_Dan	2015-05-19 08:29	25	2015-06-09 13:24	22,614
TSD subjects participation in both stages Interesting idea! Interesting idea! TSD subjects participation in both stages TSD subjects participation in both stages - ANOVA	Dr_Dan	2015-05-12 16:35	4	2015-05-13 07:33	6,942
TSDs for RSABE/ABEL TSDs for RSABE/ABEL TSDs for RSABE/ABEL TSDs for RSABE/ABEL TSDs for RSABE/ABEL TSDs for RSABE/ABEL TSDs for RSABE/ABEL - run-time Really worth the efforts?	Helmut	2015-05-06 02:17	7	2015-05-09 23:11	16,690
Advanced example (futility for GMR) Advanced example (futility for GMR) Advanced example (futility for GMR) Numbers Typos	Helmut	2015-02-27 02:03	4	2015-02-27 10:22	7,817
Gimmick & survey Gimmick & survey Gimmick & survey Gimmick & survey Speeed! Speeed! Speeed! Speeed! Speeed! Speeed! Unrolled example Unrolled example Unrolled example Increasing vector & another example Speeed!	Helmut	2015-02-20 01:47	14	2015-02-21 20:02	14,153
Type 1: n2=2 (EMA), no interim power (NL?) Type 1: no interim power (NL?) Type 1: no interim power (NL?)	Helmut	2015-02-13 13:29	2	2015-02-13 14:22	6,832
Full Replicate Study Design Full Replicate Study Design – search the Forum	prashantmohite	2015-01-28 06:56	1	2015-01-28 07:38	4,772
Two-Stage Design with Fully replicate for CANADA? Two-Stage Design with Fully replicate for Canada RSABE/TSD-combo Fully replicated-conventional ABE/TSD-combo Simulations mandatory	Rakesh_20	2015-01-22 10:26	4	2015-01-23 11:41	7,347
Interim Analysis and Power Interim Analysis and Power Interim Analysis and Power Interim Analysis and Power Interim Analysis and Power R-code & some thoughts R-code & some thoughts	Emrah Soner Özdeş	2014-12-24 07:38	6	2014-12-29 06:49	9,129
Two-stage three-treatment BE study? Bingo! Bingo! Bingo! Bingo! Terms in Anova annoying imbalance Bingo! Yes, however... Yes, however...	Oiinkie	2013-07-22 16:03	9	2014-10-31 22:20	11,785
How to find a suitable adjusted α? Suitable code for suitable adjusted α Handling inflation Potvin revis(it)ed Potvin revis(it)ed Montague revis(it)ed Pocock’s “natural constant” Pocock’s “natural constant” Another “natural constant”? Λ	Helmut	2014-05-31 18:20	9	2014-10-14 11:36	14,930
SAS code for 2-stage design SAS code for 2-stage design Phoenix/WinNonlin code maybe R too? RSABE/ABEL in a TSD: Science fiction WinNonlin 5.2.1 setup outdated software; mixed vs. fixed effects outdated software; mixed vs. fixed effects	MGR	2014-05-22 07:45	7	2014-07-03 04:32	12,746
Replicate Design Replicate Design Science fiction Science fiction Interim analysis?	Naveen Kumar	2014-06-23 13:19	4	2014-06-28 10:09	6,566
Add-on and Two-Stage Designs Add-on designs obsolete! Add-on designs obsolete! Add-on designs obsolete! Add-on designs obsolete!	Mahesh M	2014-06-17 11:12	4	2014-06-18 17:41	7,164