Bioequivalence and Bioavailability Forum

Subject	Author	Posted	Rep.	last R.	Views
differents half life values artifact? artifact? artifact? Understanding the PK of a drug	javier	2017-03-16 17:49	4	2017-03-20 13:40	8,229
AntiemeticDrug selection for BE study of Carbidopa, Levodopa and Entacapone AntiemeticDrug selection for BE study of Carbidopa, Levodopa and Entacapone AntiemeticDrug selection for BE study of Carbidopa, Levodopa and Entacapone Antiemetic Drugs can change PK profiles Antiemetic Drugs can change PK profiles Antiemetic Drugs can change PK profiles AntiemeticDrug selection for BE study of Carbidopa, Levodopa and Entacapone	anky1212	2016-12-27 14:50	6	2016-12-28 07:05	8,363
volume of distribution at steady state Vss History History Amazon? Yes. Gold Letters Gold Letters Another quest TopFit: 16bit DOS-application TopFit: less than 1.44 MB TopFit: less than 1.44 MB TopFit: less than 1.44 MB TopFit: 16bit DOS-application volume of distribution at steady state Vss: MIT is needed anyway... it seems possible for me... Leslie disagrees OK! we cannot calculate Vdss with dataset from extravascular dosing alone MRTINF includes Mean Input Time “Gravity Duration” Was Leslie wrong about Eq (8)? Leslie cannot be wrong	martin	2011-10-18 07:49	21	2016-09-26 07:43	27,022
Linear Pharmacokinetics of Levamlodipine Linear Pharmacokinetics of Levamlodipine Quantification of S-amlodipine Quantification of S-amlodipine Quantification of S-amlodipine Quantification of S-amlodipine Quantification of S-amlodipine Quantification of S-amlodipine Linear Pharmacokinetics of Levamlodipine Linear Pharmacokinetics of Levamlodipine Linear Pharmacokinetics of Levamlodipine	Mauricio Sampaio	2015-10-07 00:24	10	2016-06-12 19:48	13,106
Cumulation detection Cumulation detection	BE-proff	2015-11-24 08:13	1	2015-11-24 12:41	8,648
Why do we need AUMC? Why do we need AUMC? Do we need MRT? AUMC ⇒ MRT AUMC ⇒ MRT AUMC ⇒ MRT	BE-proff	2015-11-02 14:24	5	2015-11-02 18:43	12,039
volume of distribution at steady-state volume of distribution at steady-state volume of distribution at steady-state	Alex	2015-08-25 17:00	2	2015-08-26 12:05	7,171
Partial AUC Partial AUC and missing concentrations	Hitesh Chauhan	2015-08-19 07:47	1	2015-08-19 08:20	5,974
LLOQ/2 for BQLs not suggested Zero suggested? Interpolate? Impute? "embedded BLOQ" aka "triangular points"	Helmut	2015-06-08 12:35	4	2015-06-08 12:51	11,843
PK linearity of propranolol Learn to google! Learn to google! PK linearity of propranolol PK linearity of propranolol PK linearity of propranolol	pjs	2015-05-11 14:06	5	2015-05-12 14:58	9,352
linear kinetics following infusion? linear kinetics following infusion?	Alex	2015-04-14 12:48	1	2015-04-14 12:38	6,799
Cmax value higher than AUC Cmax value higher than AUC Cmax value higher than AUC Cmax value higher than AUC Cmax value higher than AUC Cmax value higher than AUC Cmax value higher than AUC Cmax value higher than AUC Cmax value higher than AUC Cmax value higher than AUC Magic ElMaestrolophystic RoadShow Magic ElMaestrolophystic RoadShow Magic ElMaestrolophystic RoadShow Bizarre discussion… Bizarre discussion… Cmax value higher than AUC Cmax value higher than AUC	msmnainar	2015-02-16 13:41	16	2015-02-17 19:16	19,225
optimal individualized PK sampling time points	martin	2015-02-14 10:51	0		3,367
Lottery or science? Lottery or science? Lottery or science? Lottery or science? Lottery or science? Lottery: maybe. Science: no. Lottery: maybe. Science: occasionally Lottery: maybe. Science: occasionally Lottery: maybe. Science: no. post additional studies post additional studies Historic abstract of Cmin in BE Historic abstract of Cmin in BE	nobody	2015-01-13 10:21	12	2015-01-14 07:42	13,168
enterohepatic recycling, how to calculate Kel? Kel or λz? Kel or λz? Kel or λz? Kel or λz? Kel or λz? Kel or λz? Kel or λz? Kel or λz? TOST PowerTOST Kel or λz? Kel or λz? Kel or λz?	Astea	2014-12-28 12:40	13	2014-12-31 12:41	14,961