Bioequivalence and Bioavailability Forum

Subject	Author	posted	Replies	last R.	Views
predicting in vivo PK profiles from in vitro data after establishing IVIVC external predictability for ivivc external predictability for ivivc identical pH identical pH R scripts/codes for in-vivo conc. Software validation, another round Deconvolution Software validation, another round Software validation, another round Software validation, another round Should we also consider to validate the validation? Who inspects the inspectors? Who inspects the inspectors? Sapienti sat R scripts/codes for in-vivo conc. Bioavailabity term in predicted in-vivo conc.	amer	2019-09-09 05:04	16	2019-09-13 12:59	493
Biorelevant Dissolution - FeSSGF with Ensure Plus	thalita_m	2019-07-26 15:55	0		270
BSC approach at each strength? BSC approach at each strength? BSC approach at each strength? BSC approach at each strength? BSC approach at each strength? BCS approach at each strength?	Mauricio Sampaio	2019-07-19 22:29	5	2019-07-26 15:32	524
Statistical comparison of dissolution profiles - variable nr of units Statistical comparison of dissolution profiles - variable nr of units Statistical comparison of dissolution profiles - variable nr of units EU: No Mahalanobis	MSimoes	2019-07-17 18:13	3	2019-07-18 13:06	426
Virtual Bioequivalence: a myth or coming reality? Virtual Bioequivalence: a myth or coming reality? Virtual Bioequivalence: a myth or coming reality? Virtual Bioequivalence: an update from PAGE (+TSD!) FDA not concerned about the type I error?	mittyri	2018-06-09 22:39	4	2019-06-22 18:11	2,259
IVIVC with Bioequivalence Data IVIVC or not IVIVC? IVIVC or not IVIVC? Get Fabs if no iv data...	thalita_m	2019-06-18 01:55	3	2019-06-20 22:40	755
IVIVC calculations IVIVC calculations IVIVC calculations IVIVC calculations Mergers IVIVC calculations PCDCON ⇒ IVIVC calculations IVIVC calculations IVIVC calculations Minitab etc. Minitab etc. XL XL XL XL XL Broken link XL XL XL Any news? Good News PBPK IVIVC PBPK IVIVC PBPK IVIVC Good News Contact Contact XL Jean-Michel Jean-Michel IVIVC calculations IVIVC calculations	mahendra	2013-10-24 16:10	32	2019-06-20 22:18	21,563
Is FDA dissolution database more preferable to product specific FDA BE guidance? Is FDA dissolution database more preferable to product specific FDA BE guidance?	yuvaneshwari	2019-04-18 11:12	1	2019-04-25 13:15	718
Dissolution similarity Dissolution similarity Dissolution similarity Mahalanobis distance - R code DDSolver, Mahalanobis distance and its 90% CI DDSolver, Mahalanobis distance and its 90% CI DDSolver, Mahalanobis distance and its 90% CI DDSolver, Mahalanobis distance and its 90% CI	Nirali	2010-11-10 11:13	7	2019-03-07 19:23	17,394
BCS II waiver approach No way No way	yuvaneshwari	2019-01-23 06:09	2	2019-01-28 05:16	847
A fixed dose combination dissolution evaluation discriminatory methods? discriminatory methods? discriminatory methods? A fixed dose combination dissolution evaluation A fixed dose combination dissolution evaluation A fixed dose combination dissolution evaluation A fixed dose combination dissolution evaluation A fixed dose combination dissolution evaluation	mahonny	2014-04-04 09:00	8	2018-12-05 06:27	7,751
Solubility Testing-Shake flask method	ramgopi	2018-12-03 13:30	0		698
BCS Biowaiver for oral suspension BCS Biowaiver for oral suspension BCS Biowaiver for oral suspension BCS Biowaiver for oral suspension BCS Biowaiver for oral suspension	averroes1304	2018-11-19 21:14	4	2018-11-27 03:50	1,639
Class I BCS based biowaiver with different amounts of API between T and R Class I BCS based biowaiver with different amounts of API between T and R Class I BCS based biowaiver with different amounts of API between T and R	joosefupas	2018-11-08 11:00	2	2018-11-12 09:49	1,066
EMA: Mahalanobis distance is dead... EMA: Mahalanobis distance is dead...	Helmut	2018-11-09 18:01	1	2018-11-09 19:12	1,228