Bioequivalence and Bioavailability Forum

Subject	Author	Posted	Rep.	last R.	Views
Sample size determination for William Design Williams’ design (all at once vs. two-at-a-time) Williams’ design (all at once vs. two-at-a-time)	Irene_I	2018-07-04 10:27	2	2018-07-05 09:04	5,108
Power in the pivotal study (EU) Stop estimating post hoc power! Stop estimating post hoc power! Confession Confession Confession Confession Silly-O-Meter: Syntax Silly-O-Meter: Syntax Stop estimating post hoc power! Eligible subjects? Don’t we deserve an answer?	valivetiananth	2018-05-31 13:49	11	2018-06-09 13:13	9,750
sample size in bioequivalence studies sample size in bioequivalence studies sample size in bioequivalence studies sample size in bioequivalence studies sample size in bioequivalence studies sample size in bioequivalence studies sample size in bioequivalence studies Don’t use the formula by Chow, Shao, Wang! Don’t use the formula by Chow, Shao, Wang! Don’t use the formula by Chow, Shao, Wang! Don’t use the formula by Chow, Shao, Wang! Don’t use the Book by Chow, Shao, Wang! compromised power compromised power terminology terminology terminology sample size in bioequivalence studies	daryazyatina	2017-08-03 09:34	17	2018-06-03 10:58	22,038
Power decrease for the highly correlation of AUCt and AUCinf Relevant: The PK metric with highest CV Relevant: The PK metric with highest CV Power of 2 independent TOSTs ≈ 2 simultaneous TOSTs with ρ=0 Power of 2 independent TOSTs ≈ 2 simultaneous TOSTs with ρ=0	libaiyi	2018-05-23 08:40	4	2018-05-30 01:24	6,174
BE parallel studies with more than 2 arms BE parallel studies with more than 2 arms BE parallel studies with more than 2 arms	Louis52	2018-04-18 20:18	2	2018-04-23 19:20	4,200
Levothyroxine Sample size and study design Levothyroxine Sample size and study design Levothyroxine Sample size and study design Levothyroxine Sample size and study design Levothyroxine Sample size and study design	lakshmiprasad	2018-04-11 15:09	4	2018-04-14 10:55	5,493
Power R WinNonLin Power R WinNonLin Power_TOST in PHX/WNL 6.4+ Power_TOST in PHX/WNL 6.4+ Power_TOST in PHX/WNL 6.4+ Power_TOST in PHX/WNL 6.4+ Power R WinNonLin Power of two stage design Power2Stage / power.2stage()	Yura	2018-01-23 15:02	8	2018-03-24 14:49	11,249
Within subject variability CVw pooled from CVwT and CVwR	MaggieSantos	2018-03-15 22:51	1	2018-03-16 11:56	4,921
Sample size for IVPT study	MGR	2018-02-22 06:17	0		3,692
Sample Size Estimation -Replicate design- BE limits Reference-scaling: Don’t use FARTSSIE! Reference-scaling: Don’t use FARTSSIE? Reference-scaling: Don’t use FARTSSIE! Reference-scaling: USE PowerTOST Reference-scaling: USE PowerTOST Reference-scaling: USE PowerTOST Reference-scaling: USE PowerTOST Use PowerTOST Use PowerTOST, not Endrényi L, Tóthfalusi L tables Precision in Endrényi L, Tóthfalusi L tables Precision of PowerTOST Precision of PowerTOST Precision of PowerTOST Precision of PowerTOST Precision of PowerTOST Precision of PowerTOST Reference-scaling: Don’t use FARTSSIE! Reference-scaling: Don’t use FARTSSIE!	cakhatri	2017-11-30 09:44	18	2018-02-09 19:15	17,181
Sample size for 4-period 4-sequence crossover BE study function sampleN.TOST of package PowerTOST Alpha adjustment in higher order crossover Deficiencies Deficiencies Deficiencies Deficiencies Deficiencies Deficiencies Deficiencies alpha... where is omega? α and no ω TIE for NTIDs TIE for NTIDs TIE for NTIDs TIE for NTIDs TIE for NTIDs TIE for NTIDs TIE for NTIDs TIE for NTIDs bow TIE for NTIDs bow TIE for NTIDs 111.11 for NTIDs 111.11 for NTIDs bow TIE for NTIDs	Bryony Simmons	2018-02-01 12:16	24	2018-02-06 11:34	23,699
Sample Size calculation for Clinical trials Sample Size calculation for Clinical trials	Mohamed Yehia	2018-02-04 11:42	1	2018-02-05 14:07	4,016
Finding the CI limits CV from CI CV from CI CV from CI CV from CI CV from CI	Louis52	2018-02-01 19:57	5	2018-02-05 10:39	8,217
CVwithin calculation of biperiden pooled CV from MR vs. IR pooled CV from MR vs. IR pooled CV from MR vs. IR pooled CV from MR vs. IR TSD: BE in stage 1 TSD: BE in stage 1	CECIF	2018-01-17 20:44	6	2018-01-21 02:32	5,617
Why is the bootstrap not widely used?	ElMaestro	2018-01-13 11:06	0		2,148