Bioequivalence and Bioavailability Forum

Subject	Author	posted	Replies	last R.	Views
Non-inferiority Sample Size Estimation Non-inferiority Sample Size Estimation Non-inferiority Sample Size Estimation Read, read, read!	sury	2019-04-16 08:44	3	2019-04-17 10:59	249
Sample Size Based on Pharmacodynamic endpoints Sample Size Based on Pharmacodynamic endpoints Sample Size Based on Pharmacodynamic endpoints Sample Size Based on Pharmacodynamic endpoints Sample Size Based on Pharmacodynamic endpoints Sample Size Based on Pharmacodynamic endpoints	sury	2019-04-03 12:28	5	2019-04-05 08:37	369
Deletti tables for sample size Of historic(al) interest only Of historic(al) interest only Software validation – again and again Software validation – again and again Fiaker und Apfelstrudel Fiaker und Apfelstrudel Fiaker und Apfelstrudel Fiaker und Apfelstrudel Fiaker und Apfelstrudel White-box validation White-box validation Power of Proc Power	sury	2019-03-19 12:22	12	2019-03-21 00:19	616
Chloropyramine BE study Pilot study Pilot study GRLS data GRLS data lucky sponsors	Elena777	2019-03-13 17:17	5	2019-03-14 11:28	383
Bioavailability-Sample size	pablomhdz	2019-02-06 16:45	0		390
Formulas to calculate sample size Formulas to calculate sample size Formulas to calculate sample size Hey, python is not so difficult :p experiments with a function optimization experiments with a function optimization	BE-proff	2019-02-04 12:12	5	2019-02-05 07:19	734
Sample Size calculation for ophthalmic PK endpoint study Simulations?	CBB	2019-01-30 12:06	1	2019-01-31 23:28	378
power_TOST VS statistical power of the ANOVA Power_80_20 Power_80_20 Power_80_20	MCELESTINO	2019-01-03 22:05	3	2019-01-04 21:39	623
AUC or Cmax for RSABE? Take them both	BE-proff	2018-12-24 17:58	1	2018-12-24 21:33	639
AUCsingle dose/Ctrough	Sundar.M	2018-12-20 09:30	0		439
Larger difference between upper and lower limit of 90% CI Larger difference between upper and lower limit of 90% CI	mirza baig	2018-11-28 16:14	1	2018-11-28 23:49	672
Power in case of a 3-arm BE study Power in case of a 3-arm BE study Power in case of a 3-arm BE study PowerTOST and 3-way parallel group BE study PowerTOST and 3-way parallel group BE study PowerTOST and 3-way parallel group BE study	Louis52	2018-11-14 22:40	5	2018-11-15 23:54	944
Power is getting high Power is getting high? Stop estimating post hoc power! Stop estimating post hoc power! Stop estimating post hoc power! Simulations Simulations Simulations Simulations Simulations Simulations α and 1–β α and 1–β α and 1–β α and 1–β Educate the IEC and regulators “Forced BE” 101 “Forced BE” 101 Would you be so kind answering our questions? Would you be so kind answering our questions? Yes, but why? Yes, but why? Optimists and pessimists "normal" GMR setting Example for discussion Example for discussion I prefer to play it safe Full ACK About GMR 1.10 Better 0.95 or 0.90 Yes, but why? Buffon's needle Buffon's needle 0.95 or 1.05 Buffon's needle Buffon's needle School maths School russian Offtop: Umschrift der westlichen Eigennamen auf Russisch EEU? EEU? EEU - pharmacokinetic equation??? EEU? Simulations Numbers don't lie	kms.srinivas	2017-12-26 07:39	44	2018-10-12 23:25	19,460
Lower bound for power of two combined TOST? Lower bound for power of two combined TOST? Lower bound for power of two combined TOST? Appendix D Appendix D Use of lower bound for power of two combined TOST Use of lower bound for power of two combined TOST Use of lower bound for power of two combined TOST	d_labes	2018-07-25 10:40	7	2018-08-07 11:50	1,649
Sample size calculation for CEP study	GM	2018-07-25 13:52	0		614