Bioequivalence and Bioavailability Forum

Subject	Author	Posted	Rep.	last R.	Views
Reverse Engineering → Back calculate the intra CV Why not? Why not? degrees of freedom degrees of freedom of partial replicate 2x3x3	jag009	2013-05-03 16:45	4	2025-07-04 07:20	6,772
Significance Significance Significance Quality vs. Clinical Sample size? Sample size? Sample size? Sample size, ratio, CV ↔ power Sample size, ratio, CV ↔ power Sample size, ratio, CV ↔ power TOST != treatment effect Sample size, ratio, CV ↔ power Not vice versa Not vice versa? Not vice versa? Sample size calculation using Marzo and Balant method Marzo / Balant formula Marzo / Balant formula Marzo / Balant formula Marzo / Balant formula for parallel groups	The Outlaw Torn	2012-11-20 07:56	19	2025-02-25 06:12	17,657
how to construct confidence interval for un-transformed metric? how to construct confidence interval for un-transformed metric? how to construct confidence interval for un-transformed metric? Fieller’s confidence interval Fieller’s confidence interval Fieller’s confidence interval Rescue approaching – PowerTOST Rescue approaching – PowerTOST Why not base 🇷? Why not base 🇷?	lizhao	2016-02-17 19:01	9	2025-02-15 20:42	13,262
software for calculating sample size for replicate bioequivalence studies 🇷 package PowerTOST	gsrao2022	2024-09-24 17:21	1	2024-09-24 19:33	2,389
Sequential Sample Size and Power Estimate in R IUT IUT power is analytically accessible Power<50% Power<50% Power<50%	xpresso	2023-09-19 13:40	6	2024-03-01 23:02	5,872
Sample size calculation for NTI molecules PowerTOST: sampleN.NTIDFDA() PowerTOST: sampleN.NTIDFDA() 'CVcap' sampleN.NTIDFDA(), power.NTIDFDA, pa.NTIDFDA are deprecated	narra1813	2019-08-10 09:21	4	2024-02-26 10:54	8,631
Power TOST question Power TOST question Power TOST question Total sample size vs. vector of groups sizes	Achievwin	2024-02-20 19:49	3	2024-02-23 10:06	3,913
sampleN.TOST vs. sampleN.scABEL ABEL is a framework (decision scheme) ABEL is a framework (decision scheme) ABEL vs. ABE ABEL vs. ABE Being able to read does not hurt… Being able to read does not hurt… Being able to read does not hurt… Vet BE Guideline	BEQool	2024-01-29 11:53	8	2024-02-05 16:49	6,193
Go/No-go Decision for Pivotal Study Problematic T/R-ratio… TSD? sample size for TSD is better than for 1SD?	NK	2023-12-27 12:15	3	2024-01-01 19:54	4,103
FDA: PD BE study FDA: PD BE study	balakotu	2023-07-12 04:24	1	2023-07-13 08:45	3,658
Sample size estimation for parallel design with more than 2 treatments Sample size estimation for parallel design with more than 2 treatments >2 treatments, multiplicity or not >2 treatments, multiplicity or not	BEQool	2023-05-24 21:05	3	2023-05-29 10:41	4,095
Sample Size Benefits of Replicate Design with ABE Sample Size Benefits of Replicate Design with ABE Dropouts less problematic	Sereng	2023-05-24 15:41	2	2023-05-25 16:27	3,859
R Validation R Validation R Validation R Validation	Imph	2023-05-14 13:48	3	2023-05-15 13:42	3,793
Sample size estimation for parallel design Parallel designs (total variance) Parallel designs (total variance) CV-intra # 60% CV-inter total (pooled) variance: examples total (pooled) variance: examples total (pooled) variance: examples Higher-Order Crossovers Higher-Order Crossovers total (pooled) variance: examples total (pooled) variance: examples total (pooled) variance: examples total (pooled) variance: examples total (pooled) variance: examples total (pooled) variance: examples Sample size estimation for parallel design	Nav Coelho	2007-07-20 16:14	15	2023-05-04 08:17	30,991
Sample size for replicate crossover studies Sample size for replicate crossover studies Sample size for replicate crossover studies Sample size for replicate crossover studies	Imph	2023-03-06 14:29	3	2023-03-07 11:30	4,389