Bioequivalence and Bioavailability Forum • Between

Between [PK / PD]

posted by ElMaestro – Denmark, 2013-01-23 05:52 (4109 d 17:49 ago) – Posting: # 9903
Views: 7,287

Hi John,

❝ You meant to wrote "... with no regard to within-subject variability."?

Actually, I meant between. In Potvins paper (see PubMed ref. here) the approach was to just simulate the log(T)-log(R) plusminus intrasubject variability and forget about the between-subject variability; for the purpose of her simulations this variability -just like period and sequence effects- isn't necessary.

—
Pass or fail!
ElMaestro

Complete thread:

Simulation incorporating intrasubject CV jag009 2013-01-22 21:11 [PK / PD]
- Simulation incorporating intrasubject CV ElMaestro 2013-01-22 22:59
  - Simulation incorporating intrasubject CV jag009 2013-01-22 23:13
    - BetweenElMaestro 2013-01-23 04:52
      - Between jag009 2013-01-23 15:03
- Simulation incorporating intrasubject CV Helmut 2013-01-24 06:44
  - Simulation incorporating intrasubject CV jag009 2013-01-24 19:54
    - Bootstrap? ElMaestro 2013-01-24 20:35
      - Bootstrap? jag009 2013-01-24 22:19
        
        Bootstrap? jag009 2013-01-29 16:48