Bioequivalence and Bioavailability Forum • Numerical integration

Numerical integration [Bioanalytics]

posted by drshiv – India, 2007-08-14 10:29 (6098 d 19:01 ago) – Posting: # 981
Views: 10,752

Hi HS,

Yes, you are right, trapezoidal rule is just an approximation method. I have read the paper of Yeh and Kwan way back in 1989 and used it to write programs for my PhD research. I have also used 5 part Runge-Kutta method for area calculation and also solving numerical ordinary differential equations. You have rightly put that people must use different methods to know the significance of these methods in the area of pharmacokinetics for obtaining numerical solutions.

Thanks for bringing these issues for open discussion.

Dr. Shiv

Edit: Full quote removed. Please see this post! [HS]

Complete thread:

PK Vs Analytical Charl 2007-07-23 10:44 [Bioanalytics]
- PK Vs Analytical Helmut 2007-07-23 18:04
  - PK Vs Analytical Charl 2007-07-24 10:31
    - PK Vs Analytical Helmut 2007-07-24 13:42
      - PK Vs Analytical Charl 2007-07-24 15:02
- PK Vs Analytical drshiv 2007-07-31 08:47
  - PK Vs Analytical Charl 2007-07-31 14:07
    - PK Vs Analytical drshiv 2007-08-07 16:37
      - NCA 'model independent'? Helmut 2007-08-11 20:09
        
        NCA 'model independent'? drshiv 2007-08-12 13:08
        
        Numerical integration Helmut 2007-08-12 18:51
        
        Numerical integrationdrshiv 2007-08-14 08:29