Bioequivalence and Bioavailability Forum • Unbalanced

Unbalanced [General Statistics]

posted by d_labes – Berlin, Germany, 2013-01-09 17:56 (4552 d 16:24 ago) – Posting: # 9806
Views: 8,379

Dear Helmut!

❝ With roundit=T I got 0.033605.

Me too.

❝ Same value if I switch lines 65–66 to R’s round(). With my original code I got (R’s rounding) 0.033786, but run-time was ~30 minutes.

Your observation that cround() and round() work equal if rounded to 4 decimals.

❝ BTW, couldn’t figure out how to modify the code for imbalanced sequences.

Described in the question for unbalanced designs.
Based on this:

power2.TOST(CV=0.3,n=c(4,7),theta0=1.25)

[1] 0.02718537

set.seed(123)

power.sim2x2(CV=0.3, n=c(4,7), GMR=1.25)

[1] 0.027217

—
Regards,

Detlew

Complete thread:

Imbalanced Xovers: α-inflation? Helmut 2012-12-27 17:21 [General Statistics]
- Imbalanced Xovers: α-inflation? ElMaestro 2012-12-28 09:30
  - Imbalanced Xovers: α-inflation? Helmut 2012-12-28 14:37
    - please explain ElMaestro 2012-12-29 08:44
      - I’ll try Helmut 2012-12-29 15:42
- Imbalanced Xovers: α-inflation? d_labes 2012-12-31 13:50
- One Mio sims of 2x2x2 in R in under 1 sec d_labes 2013-01-09 15:23
  - Wow! Helmut 2013-01-09 16:10
    - Unbalancedd_labes 2013-01-09 16:56
      - α-inflation ≈ urban myth Helmut 2013-01-09 18:07
        
        Beer d_labes 2013-01-10 11:07
        
        Beer Helmut 2013-01-10 13:45

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