Bioequivalence and Bioavailability Forum • Williams’ designs more reliable?

Williams’ designs more reliable? [Design Issues]

posted by Ben – Germany, 2012-11-09 19:20 (4977 d 09:35 ago) – Posting: # 9530
Views: 6,824

Dear Detlew,

❝ So what mysterious feature should let to more reliable results?

The idea was because of the fact that the number of subjects who receive formulation i in some period followed by formulation j in the next period is the same for all i # j. You don't have this in a Latin square. Note that I was not talking about 'more precise' results.

Otherwise I fully agree with what you have stated!

Thanks,
Ben

Complete thread:

Replicated cross over with fixed number of periods martin 2012-11-05 17:31 [Design Issues]
- Additional information martin 2012-11-06 11:50
  - Quick Q for my clarification ElMaestro 2012-11-06 12:09
    - Quick Q for my clarification martin 2012-11-06 12:29
      - 5 periods ElMaestro 2012-11-06 12:43
      - Latin Squares ↔ Williams’ designs Helmut 2012-11-06 14:07
        
        Latin Squares ↔ Williams’ designs Ben 2012-11-07 21:10
        
        Williams’ designs more reliable? d_labes 2012-11-08 08:29
        
        Williams’ designs more reliable?Ben 2012-11-09 18:20
        
        Williams’ designs more reliable? d_labes 2012-11-11 14:14
        
        Williams’ designs more reliable? Ben 2012-11-18 13:20
        
        Frequentists vs. Bayesians Helmut 2012-11-18 14:48
        
        Frequentists vs. Bayesians Ben 2012-11-18 15:28