Latin Squares ↔ Williams’ designs [Design Issues]

posted by Helmut Homepage – Vienna, Austria, 2012-11-06 15:07 (4161 d 00:03 ago) – Posting: # 9513
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Hi Martin!

❝ I was told that this design is standard for this kind of studies (one test and 2 references) […]



There’s a hint in EMA’s BE GL p.22 (“3 treatment, 3 period, 6 sequence design”). Williams’ designs are variance-balanced for (first-order) carry-over, which should be avoided by a suitable washout anyway. I have learned from Detlew that Latin Squares should do as well.

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