Bioequivalence and Bioavailability Forum • Sequence effect bear vs WinNonlin opposite results

Sequence effect bear vs WinNonlin opposite results [Software]

posted by yjlee168 – Kaohsiung, Taiwan, 2012-08-29 04:53 (4632 d 12:40 ago) – Posting: # 9120
Views: 7,474

Dear ElMaestro,

I think we have discussed this question about two years ago. Please see your previous comments here. Thus, why I said there was no way to calculate Type III SS with R as SAS did.

❝ PS - to yjlee: For type III SS you can use drop1 in R, or you can work around manually by adding and removing factors in the lm specification. For Seq, the latter might be the best option since Subjects are uniquely split out on Seqs. A drop1 with Subj, Seq, Per, Trt as factors will for Seq just give flat zero (plusminus some machine/convergence precision) due to the design.

—
All the best,
-- Yung-jin Lee
bear v2.9.2:- created by Hsin-ya Lee & Yung-jin Lee
Kaohsiung, Taiwan https://www.pkpd168.com/bear
Download link (updated) -> here

Complete thread:

Sequence effect bear vs WinNonlin opposite results Risherd 2012-08-27 20:39 [Software]
- Sequence effect bear vs WinNonlin opposite results yjlee168 2012-08-27 21:35
- Sequence effect bear vs WinNonlin opposite results ElMaestro 2012-08-27 22:37
  - Sequence effect bear vs WinNonlin opposite resultsyjlee168 2012-08-29 02:53
- SAS Type I/III ↔ WinNonlin partial/sequential tests Helmut 2012-08-28 14:39
- Sequence effect bear vs WinNonlin opposite results ElMaestro 2012-08-28 19:13
  - Sequence effect bear vs WinNonlin opposite results Risherd 2012-08-29 18:09
    - Division by 0.0566? ElMaestro 2012-08-29 19:42
    - Related to AUC Parameter… Tushar.g 2012-09-11 13:29