how to use Loo Riegelman method and deconvolution [Dissolution / BCS / IVIVC]
Hi Laili,
sorry for a late response but i think for loo-riegelman deconvolution you should have a look at book of Gibaldi and Perrier pharmacokinetics 2nd edition page no. 155- 162
provided parameters like
K12;
K21;
Ke or K10;
you can calculate by using following equations:-
K21=((A1*b)+(B1*a))/a+b;
Ke= (a*b)/K21;
K12= a+b-K21-Ke;
Hope it will work for you
vijay
Edit: Full quote removed. Please delete anything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Ohlbe]
sorry for a late response but i think for loo-riegelman deconvolution you should have a look at book of Gibaldi and Perrier pharmacokinetics 2nd edition page no. 155- 162
provided parameters like
K12;
K21;
Ke or K10;
you can calculate by using following equations:-
K21=((A1*b)+(B1*a))/a+b;
Ke= (a*b)/K21;
K12= a+b-K21-Ke;
Hope it will work for you
vijay
Edit: Full quote removed. Please delete anything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Ohlbe]
Complete thread:
- how to use Loo Riegelman method and deconvolution laili 2012-05-07 09:40
- how to use Loo Riegelman method and deconvolution SDavis 2012-05-18 12:32
- how to use Loo Riegelman method and deconvolutionvjkumar 2012-08-23 12:03
- how to use Loo Riegelman method and deconvolution Gobardhan 2020-07-16 13:31