Bioequivalence and Bioavailability Forum

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posted by Helmut  – Vienna, Austria, 2012-06-12 21:50 (4753 d 17:02 ago) – Posting: # 8718
Views: 12,540

Hi John!

❝ Really? I think it's more appropriate to present mean curve with arithmetic means. Can you elaborate?

No, no – like in GxP: Guilty until proven innocent! Why do you think arithmetic means are more suitable?
I myself have great difficulties accepting negative concentrations in pharmacokinetics.^* What do you prefer: negative volume or negative mass? Perhaps this is the first glimpse of the existence of exotic matter and in the near future we will be able to construct a wormhole from a test tube containing plasma.

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• A consequence of using the arithmetic mean as the minimum-variance unbiased estimator of normal distributed data.

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна! 
Helmut Schütz


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Complete thread:

• which time points to use for calculation of kel Samir Malhotra 2012-06-12 10:59 [NCA / SHAM] 
  • which time points to use for calculation of kel ElMaestro 2012-06-12 11:16
    • which time points to use for calculation of kel Samir Malhotra 2012-06-12 11:28
      • which time points to use for calculation of kel ElMaestro 2012-06-12 11:35
      • which time points to use for calculation of kel Samir Malhotra 2012-06-12 11:59
        • which time points to use for calculation of kel ElMaestro 2012-06-12 12:39
          • Wetware required Helmut 2012-06-12 15:59
            • Geometric, arithmetic, median ... ? d_labes 2012-06-12 16:28
              • Geometric, arithmetic, median ... ? Helmut 2012-06-12 17:51
                • Geometric, arithmetic, median ... ? d_labes 2012-06-13 08:53
                  • Geometric, arithmetic, median ... ? Helmut 2012-06-13 08:58
            • Wetware required jag009 2012-06-12 17:38
              • Wetware requiredHelmut 2012-06-12 19:50
            • Wetware required jag009 2012-06-12 17:40
              • Wetware required Helmut 2012-06-12 18:23
                • Wetware required Samir Malhotra 2012-06-13 09:39
                  • Fit individuals; ignore BQLs Helmut 2012-06-13 20:33