Bioequivalence and Bioavailability Forum • Common variance!

Common variance! [Design Issues]

posted by ElMaestro – Denmark, 2012-06-11 22:34 (5130 d 05:15 ago) – Posting: # 8688
Views: 11,493

Hi Jag009,

❝ I thought about adaptive design as well but then timing would become an issue since bioanalytical would be involved during the process? The stupid thing is we want to test all and hit the spot with one (hopefully). It is a resource (outsourcing) vs time issue.

And on a side note I have to say I think this is becoming almost a syndrome now in the pharma industry. Everything is being LEAN'ed into dysfunctionality where management dictates a "yes we can"-attitude which is basically founded in hot air. Another syndrome is the "fight for it"-order that top management issues when studies have gone so pearshaped that noone (except management) believes it can be accepted by the regulatory authority.
Now I've said it. It feels good. I will now take my medicine. Sorry. Back into my cage.

—
Pass or fail!
ElMaestro

Complete thread:

Curiosity: Running BE studies with more than 2 arms jag009 2012-06-11 15:01 [Design Issues]
- Common variance! Helmut 2012-06-11 16:23
  - Common variance! jag009 2012-06-11 17:25
    - Common variance! Helmut 2012-06-11 17:35
      - Common variance! jag009 2012-06-11 20:03
        
        Common variance!ElMaestro 2012-06-11 20:34
        
        Common variance! Helmut 2012-06-12 01:03
        
        Common variance! ElMaestro 2012-06-12 13:22
  - Common variance! jag009 2012-06-12 19:56
    - What if I run a study with 2 references? jag009 2012-06-12 20:00
    - Common variance! Helmut 2012-06-12 20:39
      - Two References d_labes 2012-06-13 09:11
        
        Two References jag009 2012-09-10 22:48
        
        Two treatments only d_labes 2012-09-11 08:20
  - Common variance! jag009 2012-06-13 16:08