Bioequivalence and Bioavailability Forum • Tmax in Partial replicate design

Tmax in Partial replicate design [Nonparametrics]

posted by Joshua – India, 2012-01-20 13:09 (4478 d 11:32 ago) – Posting: # 7976
Views: 13,021

Dear D_Labes,

Thank you so much for the elaborate response :-)

❝ Method 1:

❝

❝ Calculate the differences T-R for each subject and do a Wilcoxon signed rank test with these intra-subject differences, including confidence intervals based on that test.

Could you please explain me on how to calculate the difference for the treatments for each subject when the sequence is in TRR form and then go for the non parametric analysis.

Your references were very much useful. Thanks for your consideration on sending the 'R' code also.

Thank you.

—
Joshua.

Complete thread:

Tmax in Partial Replicate Design Joshua 2012-01-17 06:59
- Good question! Helmut 2012-01-17 11:34
  - Good question! Joshua 2012-01-20 11:54
    - Early exposure (+scaling?) Helmut 2012-01-20 12:56
- Tmax in Partial replicate design d_labes 2012-01-20 11:12
  - Tmax in Partial replicate designJoshua 2012-01-20 12:09
    - Intra-subject contrast (difference) d_labes 2012-01-20 12:55
      - Intra-subject contrast (difference) Joshua 2012-01-20 13:01
      - Wilcoxon for 2x2x4. "Not many things easier than that"? Astea 2023-02-14 18:44
  - Tmax in Partial replicate design mittyri 2017-01-03 23:24
    - ISC and Wilcoxon signed rank test d_labes 2017-01-04 10:21
      - ISC and Wilcoxon signed rank test in coin package mittyri 2017-01-04 14:17
        
        ISC and Wilcoxon signed rank test in coin package d_labes 2017-01-04 16:09