intra-subject correlation [Regulatives / Guidelines]
Dear Martin!
As I told you last Wednesday at the ‘debriefing’ I would need a month of spare time to retrieve them (~100,000 data pairs in various formats). I can only serve with an overview. 133 cross-over studies, 2843 subjects, AUCt or AUCτ:
![[image]](img/uploaded/image83.png)
R² of my sample has an interesting distribution…
Of course, correlation depends on the sample size* – but you get an impression.
Studies with low correlations contained one ‘outlier’ each but were still large enough to show BE (well, that was my selection bias).
Sponsors
n=24.
❝ This is extremely interesting. I would by happy if you can you provide some summary regarding the correlation between time points. (e.g. was the correlation constant over time, …).
As I told you last Wednesday at the ‘debriefing’ I would need a month of spare time to retrieve them (~100,000 data pairs in various formats). I can only serve with an overview. 133 cross-over studies, 2843 subjects, AUCt or AUCτ:
![[image]](img/uploaded/image83.png)
min 2.5% med 97.5% max
R² 0.0480 0.1905 0.6517 0.9111 0.9639
R²adj 0.0047 0.1606 0.6329 0.9022 0.9623
sample size 6 12 20 48 52
R² of my sample has an interesting distribution…
Of course, correlation depends on the sample size* – but you get an impression.
Studies with low correlations contained one ‘outlier’ each but were still large enough to show BE (well, that was my selection bias).
Sponsors

- Odeh RE. Critical values of the sample product-moment correlation coefficient in the bivariate distribution. Commun Statist–Simula Computa.192;11(1):1–26.
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Helmut Schütz
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Science Quotes
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png)
Helmut Schütz
![[image]](https://static.bebac.at/img/CC by.png)
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- Anticonservativism?! ElMaestro 2010-02-06 17:10 [Regulatives / Guidelines]
- Conservativism? Helmut 2011-11-03 21:12
- In hindsight... ElMaestro 2011-11-03 21:43
- In hindsight... Helmut 2011-11-04 01:56
- In hindsight... ElMaestro 2011-11-04 08:41
- rlnorm simulates what? d_labes 2011-11-04 09:40
- Oops. Helmut 2011-11-04 16:05
- Oops. ElMaestro 2011-11-04 16:22
- Simulation of intra-subject variability d_labes 2011-11-07 11:16
- Simulation of intra-subject variability ElMaestro 2011-11-08 11:02
- Simulation of intra-subject variability d_labes 2011-11-07 11:16
- Oops. Oops. d_labes 2011-11-25 13:54
- Another Oops. Helmut 2011-11-25 14:23
- Oops. ElMaestro 2011-11-04 16:22
- Oops. Helmut 2011-11-04 16:05
- In hindsight... Helmut 2011-11-04 01:56
- In hindsight... ElMaestro 2011-11-03 21:43
- Simul Ants questions d_labes 2011-11-04 15:46
- Simul Ants questions ElMaestro 2011-11-04 16:06
- Simul Ants questions Helmut 2011-11-04 16:09
- Liberal Conservatives d_labes 2011-11-08 11:31
- Liberal Conservatives martin 2011-11-08 20:50
- Liberal Conservatives Helmut 2011-11-08 22:56
- intra-subject correlation martin 2011-11-09 09:01
- intra-subject correlationHelmut 2011-11-25 17:16
- intra-subject correlation martin 2011-11-09 09:01
- Liberal Conservatives Helmut 2011-11-08 22:56
- Liberal Conservatives martin 2011-11-08 20:50
- Conservativism? Helmut 2011-11-03 21:12