Bioequivalence and Bioavailability Forum

Dear Detlew!

❝ ❝ “There is only one concentration after a dose which we are certain that it does not exist: zero.” ...

❝

❝ That would mean if I had taken Schützomycin once - knowing that already very very low concentrations cause it's extraordinary effects - I could fly for the rest of my life? What a nice imagination .

Here we must distinguish between PK and PD. Schützomycin is an undocumented ingredient of _Flying Oint^ment but I can give you some details: M ~400 g·mol^-1, usual dose 200 mg and almost complete (!) dermal absorption. With a half life of ~12 hours only one molecule (on the average, of course) is left in the circulation after 34 days… Unfortunately the wonderful effects diminish much much earlier. You can cross-dress as a witch and visit the Blocksberg next Walpurgis Night – I guess it’s possible to get a try-out there.

BTW, what does “OT” in the subject line mean?