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RegisterHighly variable long half life drug parallel reference scal [Design Issues]
- A drug with a very long half life, gets retained in body for a very long period, thus it requires a parallel design for establishing Bioequivalence.
- When a drug is having a very high variability, we prefer to conduct a partial replicate or a full replicate design (RTR or RTRT).
- On the other hand if a drug is highly variable and with a very long half life can we go in for a parallel study design with three groups i.e. R T and R and do the reference scaled averaging.
else how do we design this study?
Complete thread:
- Highly variable long half life drug parallel reference scalDAHK 2011-10-11 07:27 [Design Issues]
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- Highly variable long half life drug parallel add on design? Dr_Dan 2011-10-11 10:05
- HVDs/HVDPs parallel add on design? Helmut 2011-10-11 14:34
- Highly variable long half life drug parallel reference scal Helmut 2011-10-11 14:54
- Highly variable long half life drug parallel reference scal navoday 2012-06-01 17:52
- Highly variable long half life drug parallel add on design? Dr_Dan 2011-10-11 10:05
Ing. Helmut Schütz